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Clinical relevance of Ki-67 expression in bone tumors

Katia Scotlandi M.S., Massimo Serra M.S., M. Cristina Manara M.D., Daniela Maurici M.S., Stefania Benini M.S., Giuseppe Nini M.S., Mario Campanacci M.D., Nicola Baldini M.D. Article first published...

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COX-2 Inhibitor, Celecoxib, May Prevent Lung Cancer

By Anna Azvolinsky, PhD | July 6, 2011   A study in the AACR journal Cancer Prevention Research has shown evidence that celecoxib(Drug information on celecoxib), a cyclooxygenase-2 (COX-2) inhibitor,...

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When Cell-In-Cell Invaders Spell Aggressive Cancer

Discoverers of entosis propose a sinister new role for cells within cells Pop! A mammary epithelial cell detaches from the extracellular matrix, the collagenous material that binds the cells of tissues...

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Scientists have devised a new, experimental vaccine that seems to be...

Scientists have devised a new, experimental vaccine that seems to be effective at shrinking cancerous tumors in mice by up to 80 percent. The vaccine worked at shrinking similar mouse versions of...

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activation of antitumor cytotoxic T lymphocytes by fusion of patient-derived...

Experimental Oncology 27, 273-278, 2005 (December) 273 Z. Yu*, B. Ma, Y. Zhou, M. Zhang, X. Qiu, Q. Fan Center of Orthopedic Surgery Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital,...

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Humoral, Cellular Activity of MUC1 Vaccine Shrinks Tumors In Vivo

GEN News Highlights : Dec 14, 2011 Candidate combines MUC1 glycopeptide with T-helper epitope and adjuvant. Scientists report on the design of an anticancer vaccine targeting MUC1, which triggers...

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Positive feedback and tumorigenesis: A vicious circle that promotes cell...

December 21, 2011 Cancer cells are essentially immortal. The acquisition of an unlimited capacity to divide – the process of immortalization – is a central event in the genesis of tumors. Normally,...

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Study Reveals How Normal Cells Fuel Tumor Growth

Research summary: · The study shows how normal cells in tumors can enhance the growth of the tumor’s cancer cells after losing an important tumor suppressor gene called Pten. · The findings suggest a...

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Previously unconnected molecular networks conspire to promote cancer

Inflammatory signaling blocks NUMB’s ability to deaden NOTCH1-driven tumor development HOUSTON — An inflammation-promoting protein triggers deactivation of a tumor-suppressor that usually blocks cancer...

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Possible Anti-Cancer Target: Enzyme That Flips Switch on Cells’ Sugar Cravings

research has shown that cancer cells tend to take up more glucose than healthy cells. Researchers are increasingly interested in exploiting this tendency with drugs that target cancer cells’ altered...

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